heparan sulfate

Glypican-3 ( GPC3) is a heparan sulfate proteoglycan that is bound to the cell membrane by a glycosylphosphatidylinositol ( GPI) anchor, which is a member of Glypicans family.

Glypican-3（GPC3）为膜性硫酸乙酰肝素多糖蛋白，通过糖基磷脂酰肌醇（GPI）结合于细胞表面，是硫酸类肝素糖蛋白聚糖（glypican）家族成员。

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Synergic effect of heparan sulfate and cytokines on in vitro growth of human umbilical cord blood hematopoietic cells

硫酸乙酰肝素协同细胞因子对脐血造血细胞体外生长的作用

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These heparan sulfate proteoglycans expressed cl-early the heterogeneity, because their molecular weights are 230, 8.3 and 330 kDa respectively.

这种蛋白多糖表现出明显的不均一性。因为三种分子硫酸乙酰肝素蛋白多糖的分子量分别是230、8.3和330kDa。

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Heparin Interaction between heparin/ heparan sulfate and protein

肝素/硫酸类肝素与蛋白质的相互作用

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Heparan sulfate is a typical kind of glycosaminoglycan ( GAG), having complex structures and charged with many particular biological activities.

硫酸类肝素是一种结构十分复杂，承担着多种独特生物功能的糖胺聚糖。

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Our laboratory have found that human aortic heparan sulfate proteoglycan ( HSPG) can suppress the proliferation of cultured fetal aortic smooth muscle cells ( hASMC).

本室以往的研究发现硫酸乙酰肝素蛋白聚糖对培养的胎儿主动脉平滑肌细胞的增殖有明显的抑制作用。

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Loss of cell-surface heparan sulfate expression in both cervical intraepithelial neoplasm and invasive cervical cancer

宫颈上皮内瘤样病变和浸润性宫颈癌均可发生细胞表面硫酸乙酰肝素表达缺失

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PurposeTo prepare heparan sulfate ( HS ) from different sources, and to determine their physicochemical properties.

目的从不同来源制备硫酸乙酰肝素 ( HS ), 并测定其理化性质.

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Heparan sulfate proteoglycan ( HSPG) expression in intima of aorta was determined by immunohistochemical method.

HE染色及免疫组织化学检测主动脉内膜硫酸乙酰肝素蛋白多糖（HSPG）表达。

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The reason for the blood flowing without thrombosis in vesseles is that there is the anticoagulant substances-heparan sulfate ( Heparan Sulfate, HS) expressed in the surface of vascular endothelial cells contacted with blood directly.

血液持续在血管中流动而不发生血栓的原因在于与血液直接接触的血管内皮细胞表面表达有与Hep类似的抗凝物质&硫酸乙酰肝素（Heparan Sulfate，HS）。

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The inhibitory effect of heparan sulfate on the proliferation of MDA-MB-231 cells

硫酸乙酰肝素在MDA-MB-231细胞增殖抑制中的作用

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Heparin and heparan sulfate are linear polysaccharides consisting of repeating disaccharide units of uronic acid –( 1 4)-D-glucosamine.

肝素和硫酸乙酰肝素是由糖醛酸一（1&4）一D一氦基葡萄糖的重复二糖单元组成的线性多糖。

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Study of bovine adrenocortical cells synthetize heterogeneous heparan sulfate proteoglycans

牛肾上腺皮质细胞合成蛋白多糖的研究

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Heparan Sulfate ( HS) is involved in many pathological processes of breast cancer. With the deep insights of the mechanism of growth factors modulated by HS, the research and development of heparan sulfate polysaccharide analogs became the hotspot.

硫酸乙酰肝素（Heparan Sulfate，HS）参与乳腺癌发生和发展的多个环节，随着HS对细胞生长因子调节机制研究的深入，HS多糖类似物的研发已经成为当前研究的热点。

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Relationship between distribution and change of heparan sulfate proteoglycan and atherogenesis in human coronary arteries

人冠状动脉硫酸乙酰肝素蛋白聚糖的分布和变化与动脉粥样硬化形成的关系

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Objective To review the relationship between heparan sulfate proteoglycan ( HSPG) and angiogenesis.

目的综述硫酸乙酰肝素蛋白聚糖（heparan sulfate proteoglycan，HSPG）与血管形成的关系。

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In the present investigation, effect of bitter gourd on streptozotocin-induced diabetic rats with particular emphasis on kidney heparan sulfate ( HS) was studied.

本研究重点观察苦瓜对链脲霉素诱导的糖尿病大鼠肾脏硫酸类肝素的调节作用。

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Heparanase is the only mammalian heparan sulfate-degrading enzymes; it could cleave heparan sulfate ( HS) which links to heparan sulfate proteoglycans ( HSPGs).

乙酰肝素酶是目前发现的哺乳动物细胞中唯一能切割细胞外基质中硫酸肝素蛋白多糖侧链的内源性糖苷酶。

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Some studies suggested that it may be related to the action of ameliorating the synthesis of heparan sulfate proteoglycans ( HSPG), and then suppressing the loss of anionic sites of glomerular basement membranes ( GBM) of diabetic rats.

也有研究认为，TZD与改善硫酸乙酰肝素原多糖（HSPG）合成及硫酸化、从而抑制肾小球基膜（GBM）外疏松层的阴离子位点有关。

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Development progresses of heparan sulfate polysaccharide analogs with anti-breast cancer activity

硫酸乙酰肝素多糖类似物的抗乳腺癌活性研究进展

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The action of transforming growth factor β_1 on the synthesis of heparan sulfate proteoglycans

转化生长因子β1刺激蛋白多糖的合成

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Effect of Human Aortic Heparan Sulfate Proteoglycan on the Proliferation of Cultured Cells of Human Vascular Wall

人主动脉硫酸乙酰肝素蛋白聚糖对培养的人血管壁细胞生长的作用

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Objective To explore the association between the heparan sulfate proteoglycan gene ( HSPG) polymorphism and diabetic nephropathy in Chinese.

目的探讨硫酸乙酰肝素蛋白多糖基因（HSPG）多态性与中国汉族人2型糖尿病肾脏并发症之间的关系。

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Chemical Basic of the Inhibition of Calcium Oxalate Stones by Heparin and Heparan Sulfate

肝素和硫酸乙酰肝素抑制草酸钙结石形成的化学基础

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Studies show that amyloid A fibril, amyloid enhancing factor, amyloid P component, apolipoprotein E and heparan sulfate proteoglycans may take part in the occurrence and development of the disease.

淀粉沉积物中的淀粉样A纤维以及淀粉样物促进因子、淀粉样P物质、载脂蛋白E、硫酸肝素蛋白多糖等成份参与了疾病的发生与发展。

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HSPGs are glycoproteins mainly consisting of a protein core and side chains of several linear heparan sulfate ( HS) covalent linking to the protein core.

HSPGs主要由一个蛋白核心和数个与之共价连接的线性硫酸乙酰肝素（Heparan Sulfate，HS）侧链组成。

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Heparan sulfate proteoglycan ( HSPG) is the major molecular constituents of ECM and BM, its breakdown will make it easier for tumor to occur invasion and metastasis.

近年的研究提示，硫酸肝素糖蛋白（heparan sulfate proteoglycan，HSPG）是阻止肿瘤细胞转移和扩散屏障的重要构成成分，对其降解将破坏细胞外基质和基底膜的结构，促进肿瘤浸润和转移。

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Aim To observe the anti-tumor activity and the mechanism of heparan sulfate proteoglycan ( HSPG) on C3H mice transplanted tumors.

目的观察硫酸乙酰肝素蛋白聚糖（HSPG）对C3H小鼠乳腺癌移植瘤的抑制作用及其机制。

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